LOCAL TUMOR CONTROL WITH SALVAGE CRYOTHERAPY FOR LOCALLY RECURRENT PROSTATE CANCER AFTER EXTERNAL BEAM RADIOTHERAPY
| Autor: | Edward J. McGuire, Shellie M. Scott, Louis L. Pisters, Jonathan I. Izawa, Lydia T. Madsen, Graham F. Greene, Paul Perrotte, Andrew C. von Eschenbach, Lawrence B. Levy |
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| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
Prostate biopsy medicine.diagnostic_test business.industry Urology medicine.medical_treatment Salvage therapy Cryotherapy medicine.disease Surgery Radiation therapy Prostate-specific antigen Prostate cancer medicine.anatomical_structure Prostate medicine External beam radiotherapy business |
| Zdroj: | Journal of Urology. 165:867-870 |
| ISSN: | 1527-3792 0022-5347 |
| Popis: | Purpose: We identified variables associated with a positive prostate biopsy after salvage cryotherapy in patients in whom initial external beam radiotherapy for prostate cancer failed to improve our cryotherapy technique, optimize local control and improve our patient selection criteria for salvage cryotherapy.Materials and Methods: Between July 1992 and January 1995, 145 patients underwent salvage cryotherapy. Post-cryotherapy sextant prostate biopsies were performed in 107 cases. We evaluated certain variables on univariate and multivariate analysis as predictors of a positive biopsy after cryotherapy, including the type of previous therapy, tumor stage and grade at initial diagnosis, prostate volume, pre-cryotherapy prostate specific antigen (PSA), number of positive biopsy cores before cryotherapy, PSA nadir after cryotherapy, stage and grade of local recurrence, number of cryoprobes, number of freeze-thaw cycles and use of a urethral warming catheter during cryotherapy.Results: Biopsies were positive... |
| Databáze: | OpenAIRE |
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