Quantitativ evaluierte dynamische Magnetresonanztomographie bei chronischer Polyarthritis des Kniegelenkes

Autor:	Sieper J, König H, Wolf Kj, X. Bolze
Rok vydání:	1992
Předmět:	medicine.medical_specialty medicine.diagnostic_test business.industry Pannus Magnetic resonance imaging Knee Joint medicine.disease Intra articular Prednisolone Medicine Radiology Nuclear Medicine and imaging Polyarthritis Radiology Cortisone business After treatment medicine.drug
Zdroj:	RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 157:140-144
ISSN:	1438-9010 1438-9029
DOI:	10.1055/s-2008-1032986
Popis:	32 patients with chronic polyarthritis were examined by MRT. Following intra-articular application of 25 mg prednisolone, 18 patients were re-examined after two of three weeks and 7 out of 18 patients were re-examined after 8 to 16 weeks, both by MRT and clinically. After an initial double echo sequence, we carried out a dynamic series of FLASH measurements (TR 30, TE 10 ms, 70 degrees) following an intravenous bolus of 0.1 mmol gadolinium-DTPA. Single intensity-time curves were treated quantitatively in relation to the pannus, muscles and effusions. Two or three weeks after treatment the curve parameters showed a reduction in pannus vascularisation which remained constant for the 8 to 16 weeks of further observation. Contrast diffusion in the pannus is initially reduced but approaches the early measurements at the time of the second examination.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fc98e7ab1ad3dca76861574e7feba3a6 https://doi.org/10.1055/s-2008-1032986 Zobrazit plný text záznamu