Immediate Breast Reconstruction does not Delay Adjuvant Chemotherapy nor affect Clinical Outcome

Autor: Ho Sym, Cheong Ec, Chen Jc, Lu Qs, Chan Myp, Thambiah M, Tan Ey, Seah Dw
Rok vydání: 2017
Předmět:
Zdroj: Breast Cancer: Current Research.
ISSN: 2572-4118
DOI: 10.4172/2572-4118.1000118
Popis: Background: Post-operative complications are more frequent after immediate breast reconstruction and there are concerns that it adversely affects clinical outcome. Objectives: We reviewed the rate of early and late complications after immediate breast reconstruction and evaluated their impact on adjuvant treatments and outcome. Methods: Retrospective review was performed of 146 women who underwent immediate breast reconstruction after mastectomy for breast cancer from 1st January 2001 to 31st December 2010. Results: Median patient age was 46 years and all women had no major co-morbidities. More than half the women had early-stage cancers. Reconstruction was performed with a pedicled transrectus abdominis myocutaneous flap in 109 patients, a latissimus dorsi flap in 29, a free deep inferior epigastric perforator flap in 4 and implants were inserted in 4 patients. Two patients suffered a cerebrovascular accident and one a cardiac event but all recovered fully. Early post-operative wound complications within 30 days of surgery occurred in 25 patients (17%). All, except one, were managed conservatively. Late complications occurred in 18 patients and 7 patients underwent further surgery, which most often involved abdominal hernia repair. Complications were more frequent in older patients, diabetics and those with implants inserted (P
Databáze: OpenAIRE