Incidental carcinoma of gallbladder in north India: is routine histopathology of all cholecystectomy specimens justified?
| Autor: | Vijayata Sangwan, Amrita Duhan, Mukesh Sangwan, Mohinder Kumar Garg, Deepak Singla, Pushpender Malik |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Gallbladder medicine.medical_treatment General surgery Gallstones medicine.disease Gallbladder perforation medicine.anatomical_structure Metaplasia medicine Carcinoma Cholecystectomy Histopathology medicine.symptom business Xanthogranulomatous Cholecystitis |
| Zdroj: | International Surgery Journal. :465-470 |
| ISSN: | 2349-3305 |
| DOI: | 10.18203/2349-2902.isj20150949 |
| Popis: | Background: Gallstones can cause varied spectrum of histopathology. Xanthogranulomatous cholecystitis and metaplasia have been shown to have association with carcinoma gallbladder. Incidental carcinoma of the gallbladder is a nightmare for the patient. Routine histopathology of all cholecystectomy specimens is an effective policy for its early diagnosis and management. Methods: It is a retrospective study of histopathology of cholecystectomy specimens related to gallstones disease done at a rural government in north India. All patients with preoperative or intraoperative gross malignancy of gallbladder were excluded from study. Results: In our study, females were predominating over males with a ratio of 6.07:1. The mean of all patients was 44.16±14.64 years. Chronic cholecystitis was most common (69.81%) histopathological entity. Incidental carcinoma was also revealed in 1.9 % of the cases. Metaplasia and xanthogranulomatous cholecystitis was reported in about 6% cases. Mixed stones were most common type reported in 76.79% cases. Multiple stones (72.8%) were more common than single stones. Majority (58%) of the cases in our study were operated by laparoscopic technique. Gallbladder perforation was most common complication noticed in about 4.15% cases. Conclusions: Despite meticulous preoperative investigations and gross specimen examination, incidental carcinoma of gallbladder is a rule rather than exception in significant number of cases. A routine histopathology of specimen should be considered especially in high risk zones of carcinoma gallbladder. |
| Databáze: | OpenAIRE |
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