Extrapontine myelinolysis associated with severe hypernatremia in infancy
| Autor: | Tetsuji Morimoto, Yuno Takahashi, Tatsuo Fuchigami, Ryoji Aoki, Shori Takahashi, Hiroshi Saito |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pediatrics
medicine.medical_specialty Extrapontine myelinolysis medicine.diagnostic_test business.industry Magnetic resonance imaging medicine.disease Abnormal involuntary movement Impaired consciousness 03 medical and health sciences 0302 clinical medicine 030225 pediatrics parasitic diseases Pediatrics Perinatology and Child Health Severity of illness medicine Central pontine myelinolysis Brain magnetic resonance imaging Hypernatremia business 030217 neurology & neurosurgery |
| Zdroj: | Pediatrics International. 58:936-939 |
| ISSN: | 1328-8067 |
| DOI: | 10.1111/ped.13042 |
| Popis: | Extrapontine myelinolysis (EPM) is an uncommon disorder in children, with few pediatric cases reported to date. We report the first case of an infant with EPM without central pontine myelinolysis (CPM) presenting with severe hypernatremia. On admission, the infant had impaired consciousness, mild dehydration, and severe hypernatremia (190 mmol/L). The following day, the patient developed abnormal involuntary movements. Brain magnetic resonance imaging (MRI) confirmed EPM without CPM. He recovered without sequelae, and clinical examinations were within normal limits approximately 6 months after discharge. Brain MRI at 1 year after onset showed complete disappearance of the previous EPM regions. To the best of our knowledge, this represents the youngest patient with EPM without CPM presenting with severe hypernatremia. Given that treatment for osmotic demyelination syndrome (ODS) is yet to be established, preventing the development of ODS is crucial. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text