Stimuli-responsive properties of special micellar nanocarriers and their application for delivery of vitamin E and its analogues
| Autor: | M. Ignatovskaya, V. I. Maksin, O. Iakubchak, Dmytro Klymchuk, Tatyana Zheltonozhskaya, N. M. Permyakova |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Aqueous solution
Polymers and Plastics Ethylene oxide Chemistry Hydrogen bond 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Micelle 0104 chemical sciences chemistry.chemical_compound Colloid and Surface Chemistry Polymer chemistry Materials Chemistry Copolymer Physical and Theoretical Chemistry Nanocarriers 0210 nano-technology Acrylic acid Macromolecule |
| Zdroj: | Colloid and Polymer Science. 296:295-307 |
| ISSN: | 1435-1536 0303-402X |
| Popis: | Stimuli-responsive micelles were formed by asymmetric diblock and triblock copolymers, which comprised chemically complementary (methoxy)poly(ethylene oxide) and poly(acrylic acid) blocks of different length. They were used as nanocarriers to encapsulate and deliver in vivo a poorly soluble homolog of α-tocopheryl acetate (α-TOCAh), commonly known as an analogue of vitamin E. Self-assembly of the copolymer macromolecules into special micellar structures in aqueous solutions depended on the solution pH. The micellar structures arising at pH |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink