Synthesis of the spiroacetal fragments of spirofungins A and B, antibiotics isolated from Streptomyces violaceusniger Tü 4113

Autor: Hiromasa Kiyota, Hiroyuki Sakauchi, Shigefumi Kuwahara, Yuko Asamitsu, Yuko Shimizu, Mikiko Kojima, Emi Higashi, Minoru Izumi
Rok vydání: 2015
Předmět:
Zdroj: Heterocyclic Communications. 21:337-343
ISSN: 2191-0197
0793-0283
DOI: 10.1515/hc-2015-0193
Popis: The spiroacetal [C(9)–C(20)] fragments of spirofungins A and B, antibiotics isolated from Streptomyces violaceusniger Tü 4113, were prepared from a known bromo alcohol derived from (S)-citronellal, using thermodynamically controlled iodolactonization and spiroacetalization as the key steps.
Databáze: OpenAIRE