Marasmane and normarasumane sesquiterpenenoids from the edible mushroom Russula nigricans
| Autor: | Surisa Kongthong, Masahiko Isaka, Sarunyou Wongkanoun, Arunrat Yangchum |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Russula nigricans
biology 010405 organic chemistry Bacillus cereus Plasmodium falciparum Plant Science 010501 environmental sciences biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Microbiology Mycobacterium tuberculosis Edible mushroom Bioassay Candida albicans Agronomy and Crop Science 0105 earth and related environmental sciences Biotechnology Enterococcus faecium |
| Zdroj: | Phytochemistry Letters. 21:174-178 |
| ISSN: | 1874-3900 |
| DOI: | 10.1016/j.phytol.2017.06.013 |
| Popis: | Three new marasmane sesquiterpenes, russulanigrins A–C ( 1 – 3 ), and a new normarasmane, russulanigrin D ( 4 ), together with six known sesquiterpenes, 5 , 6 , isolactarorufin ( 7 ), 8 , lactarorufin A ( 9 ), and 10 , were isolated from fruiting bodies of the edible mushroom Russula nigricans . The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. Compounds 4 , 5 , and 7 were inactive in several biological assays: anti-bacterial ( Bacillus cereus and Enterococcus faecium ), anti-mycobacterial ( Mycobacterium tuberculosis H37Ra), anti-plasmodial ( Plasmodium falciparum K1), and anti-fungal ( Candida albicans ) activities, and cytotoxicity to cancer cell-lines (KB, MCF-7, and NCI-H187). |
| Databáze: | OpenAIRE |
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