ANALGESIC ACTIVITY OF ETHANOLIC EXTRACT OF FICUS GLOMERATA LEAVES: IN VIVO EVALUATION

Autor: Kumbhar St, Pawar Yd, Shaikh Aa, Chavan Dl, Ghaisas Mm
Rok vydání: 2012
Předmět:
Zdroj: International Journal of Research in Ayurveda and Pharmacy. 3:706-709
ISSN: 2277-4343
DOI: 10.7897/2277-4343.03525
Popis: There are numerous plants which are used in Ayurveda and other t raditional system of medicine but their claim is not yet evaluated scientifically in lab oratory animals. Present study was inten ded to evaluate an analgesic activity of a Ficus glomerata leaf extract in mice to confirm ethnomedical claim made by traditional health practionars . Plant was obtained from the natives of Pune district and aut henti cated at Botanical Surve y of India , Pune. Dried leaves of a plant were extracted in ethanol using Soxhlet extractor . Ethanolic extract was evaporated using rota evaporator and stored at co ol and dry place. Extract was orally administered in mice (125mg/kg, 250mg/kg and 500mg/kg) and evaluated usi ng hot plate and tail immersion method s. Pentazocine (10 mg/kg) was taken as a standard drug. Significant analgesic activity comparable with standard dose of pentazocine was observed in both the cases. This confirms ethnomedical claim of some workers regar ding an analgesic activity of the plant.
Databáze: OpenAIRE