Nitrosylsulfuric acid in the synthesis of 5-chloroisoxazoles from 1,1-dichlorocyclopropanes

Autor:	Nikolai V. Zyk, Zaur M. Garaev, Svetlana V. Gutorova, Arseniy I. Komarov, Oksana B. Bondarenko, Lyubov I. Kuznetsova, Dmitry A. Skvortsov
Rok vydání:	2019
Předmět:	Nitrosylsulfuric acid chemistry.chemical_compound chemistry 010405 organic chemistry Reagent General Chemistry 010402 general chemistry Cytotoxicity 01 natural sciences Combinatorial chemistry 0104 chemical sciences
Zdroj:	Mendeleev Communications. 29:419-420
ISSN:	0959-9436
Popis:	Nitrosylsulfuric acid is shown to be a usable reagent for the synthesis of 5-chloroisoxazoles from readily available 1,1-di-chlorocyclopropanes via nitrosation–heterocyclization reaction. A cytotoxicity of some of the prepared 5-chloroisoxazoles towards MCF7, A549, HEK293T and VA13 cell lines was evaluated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fbf2d20256ca5092b0287d6c9a8dea48 https://doi.org/10.1016/j.mencom.2019.07.021 Zobrazit plný text záznamu Full Text from ScienceDirect