Comparison of 3-, 5-, and 7-day post-treatment evaluation periods for measuring therapeutic response to tilmicosin treatment of bovine respiratory disease

Autor:	Carter, Brandon L., McClary, David G., Mechor, Gerald D., Christmas, Rodney A., Corbin, Marilyn J., Guthrie, Carl A.
Jazyk:	angličtina
Rok vydání:	2006
Předmět:	medicine.medical_specialty Randomization medicine.drug_class business.industry Antibiotics Bovine respiratory disease medicine.disease Treatment failure chemistry.chemical_compound Pharmacotherapy chemistry Internal medicine medicine Potency Tilmicosin Post treatment business
DOI:	10.21423/bovine-vol40no2p97-102
Popis:	Three-hundred steer calves with clinical signs of bovine respiratory disease (BRD) and a rectal temperature of 104øF (40øC) or greater were enrolled in a 56-day study to evaluate the effect of a 3-, 5- or 7-day post-treatment evaluation (PTE) period on therapeutic response to tilmicosin. Trial calves (average weight 557 lb; 253 kg) were purchased from livestock auction markets in Colorado, Kansas, Oklahoma and Wyoming, and delivered to the trial site in Wellington, Colorado. Upon randomization to a treatment group, tilmicosin was administered at 4.55 mg/lb (10 mg/kg) of body weight. Three treatment groups were defined by the number of days (3, 5 and 7) post-treatment during which they were not eligible for retreatment for BRD. The 7-day PTE group had a significantly higher treatment success rate compared to the 3-day PTE group (P=0.05). The 3-day PTE group had a higher (P The Bovine Practitioner, Vol. 40, No. 2 (2006 Summer)
Databáze:	OpenAIRE
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