ChemInform Abstract: Development of a Method for the Preparation of α-Azido-Masked Acyl Cyanides, Synthetic Equivalents of N-Protected-C-Activated α-Amino Acids

Autor:	Touru Ibaragi, Hisao Nemoto, Rujian Ma, Masayuki Shibuya, Ichiro Suzuki
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Equivalent Chemistry Reagent Cyanide General Medicine Azide Threonine Bond formation Medicinal chemistry Amino acid
Zdroj:	ChemInform. 31
ISSN:	1522-2667 0931-7597
Popis:	A method for the preparation of α-azido-masked acyl cyanides as synthetic equivalents of N-protected–C-activated α-amino acids was developed using carbon–carbon bond formation between aldehydes and the Masked Acyl Cyanide Reagents, followed by sulfonylation and substitution by azide anion. This method was applied to the synthesis of d -threonine and l -allo-threonine derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fbbfed5c05f375e68949abb3a4eb9277 https://doi.org/10.1002/chin.200027075 Zobrazit plný text záznamu Plný text