Study of biocompatibility effect of nanocarbon particles on various cell types in vitro
| Autor: | Volodymyr F. Korolovych, Peter Scharff, Matthias Epple, Kateryna Loza, M. Tolkachov, Viktoriya Sokolova, Y. Prylutskyy, Uwe Ritter |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Biocompatibility biology Mechanical Engineering Mesenchymal stem cell Nanoparticle Nanotechnology 02 engineering and technology 021001 nanoscience & nanotechnology Condensed Matter Physics biology.organism_classification HeLa 03 medical and health sciences 0302 clinical medicine Mechanics of Materials 030220 oncology & carcinogenesis Cancer cell Biophysics General Materials Science MTT assay Stem cell 0210 nano-technology Cytotoxicity |
| Zdroj: | Materialwissenschaft und Werkstofftechnik. 47:216-221 |
| ISSN: | 0933-5137 |
| DOI: | 10.1002/mawe.201600486 |
| Popis: | The viability of primary cells (human mesenchymal stem cells, hMSC, as a model for healthy cells) and a cancer cell line (human transformed cervix epithelial cells, HeLa, as a model for cancer cells) was studied with the MTT assay after the incubation with water-soluble C60 fullerenes and multi-walled carbon nanotubes filled by iron, respectively. The size of the particles was determined by dynamic light scattering. The morphology of the cells incubated with nanocarbon particles was studied by scanning electron microscopy. The effect of C60 fullerenes and Fe-multi-walled carbon nanotubes on the cells is depending on the concentration of applied nanoparticles. |
| Databáze: | OpenAIRE |
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