An expedient synthesis of enantioenriched substituted (2-benzofuryl)arylcarbinols via tandem Rap–Stoermer and asymmetric transfer hydrogenation reactions

Autor:	Ragam Raju, Gullapalli Kumaraswamy, Mogilisetti Padmaja, Gajula Ramakrishna
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Salicylaldehyde Tandem Chemistry Organic Chemistry Drug Discovery Organic chemistry Benzofuran Transfer hydrogenation Biochemistry Catalysis
Zdroj:	Tetrahedron. 66:9814-9818
ISSN:	0040-4020
DOI:	10.1016/j.tet.2010.10.074
Popis:	An expedient synthesis of enantioenriched substituted (benzofuran-yl)-aryl and heteroaryl carbinols, is described. A key feature of this protocol is synthesis of functionally varied benzofuran scaffolds via a Rap–Stoermer reaction/catalytic asymmetric transfer hydrogenation (ATH) using substituted salicylaldehyde and α-haloaryl, heteroaryl ketones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fb83a1722a0d771567668e59323fee6d https://doi.org/10.1016/j.tet.2010.10.074 Zobrazit plný text záznamu Full Text from ScienceDirect