On the possibility of regulating the rate of enzymatic destruction of chitosan in an acetic acid solution
| Autor: | I. F. Tuktarova, Elena Kulish, V. V. Chernova |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
010304 chemical physics
Sodium Intrinsic viscosity Inorganic chemistry chemistry.chemical_element Electrolyte 010402 general chemistry 01 natural sciences Michaelis–Menten kinetics Polyelectrolyte 0104 chemical sciences Chitosan chemistry.chemical_compound Film coating chemistry Chemical engineering 0103 physical sciences medicine Physical and Theoretical Chemistry Swelling medicine.symptom |
| Zdroj: | Russian Journal of Physical Chemistry B. 11:338-342 |
| ISSN: | 1990-7923 1990-7931 |
| Popis: | The enzymatic destruction of chitosan in an acetic acid solution in the presence of sodium chloride and sulfate was considered. It was shown that the addition of these low-molecular electrolytes is accompanied by a tightening of the macromolecular coil, as indicated by a decrease in the α constant in the Mark–Kuhn–Houwink equation and the intrinsic viscosity of chitosan. As a consequence, the chitosan units become less accessible for interaction with the enzyme, and the kinetic parameters of the process (Michaelis constant K M and the maximum rate of enzymatic destruction V max) change accordingly. This suggests that the resistance of this polymer to the enzyme action can be enhanced by introducing low-molecular electrolyte salts in the solution or film coating to suppress the polyelectrolyte swelling of chitosan. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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