Levorphanol in the Perioperative Setting: Decreasing Opioid Requirements While Improving Pain Management
| Autor: | Sergio D. Bergese, Ana Mavarez-Martinez, Carlos Andres Perez, Sara Khan, Christopher R. Page |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Opioid use Perioperative Pain management Food and drug administration 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Opioid 030202 anesthesiology medicine Levorphanol Intensive care medicine business 030217 neurology & neurosurgery medicine.drug Experimental pharmacology Methadone |
| Zdroj: | Journal of Pain Research. 13:2721-2727 |
| ISSN: | 1178-7090 |
| Popis: | Levorphanol is a Food and Drug Administration (FDA)-approved long-acting opioid. Most information on perioperative use of levorphanol comes from the early- and mid-1950s when this drug emerged in the field of experimental pharmacology and anesthesia. It was mainly studied during this period with some additional data being generated in the 1960s and 70s. Since this time, perioperative use has declined and research is limited. This review of literature aims to provide pharmacologic and historic description of levorphanol as a tool for perioperative pain management and as an aid to potentially decrease total postoperative opioid use during the current opioid crisis. |
| Databáze: | OpenAIRE |
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