Predictive models for the overall 5-endo-trig iodocyclisation of homoallylic alcohols

Autor:	David W. Knight, Gordon G. Weingarten, Jenny M. Barks, Christopher J. Seaman
Rok vydání:	1994
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Chemistry Alkene Organic Chemistry Drug Discovery Organic chemistry Alcohol Stereoselectivity Acetonitrile Biochemistry
Zdroj:	Tetrahedron Letters. 35:7259-7262
ISSN:	0040-4039
DOI:	10.1016/0040-4039(94)85376-2
Popis:	Iodoetherifications of all isomers of the 3-methylalk-4-en-2-ols [14∼17] proceed with excellent levels of stereoselectivity, leading to tetrasubstituted tetrahydrofurans [18∼22], via overall anti-addition to the alkene function.
Databáze:	OpenAIRE
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