An efficient synthesis of a key intermediate for optically active 5,6--carbapenem antibiotics

Autor:	Yasuhiko Kawano, Norikazu Tamura, Kouichi Yoshioka, Yoshihiro Matsushita, Michihiko Ochiai
Rok vydání:	1986
Předmět:	Bicyclic molecule Intramolecular reaction Stereochemistry Organic Chemistry Regioselectivity Optically active Biochemistry chemistry.chemical_compound chemistry Carbapenem Antibiotics Intramolecular force Drug Discovery polycyclic compounds Lactam Aldol condensation
Zdroj:	Tetrahedron Letters. 27:3749-3752
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)83870-8
Popis:	A versatile intermediate (18) for optically active 5,6- cis -carbapenem antibiotics was synthesized with a highly regioselective intramolecular aldol condensation as a key step.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fb4ad43aa4c8eda1e7c9d4bae4366429 https://doi.org/10.1016/s0040-4039(00)83870-8 Zobrazit plný text záznamu