Reversed-phase ion-pair high-performance liquid chromatography assay of polyprenyl diphosphate oligomer homologues
| Autor: | Leonid L. Danilov, Vyacheslav V. Kozlov |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Chromatography 030102 biochemistry & molecular biology Active components Filtration and Separation Ion pairs Phosphate Oligomer High-performance liquid chromatography Analytical Chemistry 03 medical and health sciences chemistry.chemical_compound chemistry Reagent Phase (matter) Phosprenyl |
| Zdroj: | Journal of Separation Science. 39:525-527 |
| ISSN: | 1615-9306 |
| Popis: | A reversed-phase ion-pair high-performance liquid chromatography procedure was developed for the separation of polyprenyl diphosphate oligomer homologues obtained chemically from plant polyprenols. Tetrabutylammonium phosphate was used as the ion-pair reagent, and the dependence of the separation quality on pH of ion-pair reagent was investigated for the first time. The procedure is applicable for the control of commercial available polyprenyl monophosphates (the active components of veterinary drugs Phosprenyl and Gamapren) for the possible presence of polyprenyl diphosphate byproducts. |
| Databáze: | OpenAIRE |
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