Mitomycin-C as a Preventive Measure of Adhesion after Functional Endoscopic Sinus Surgery (FESS)
| Autor: | Doaa Abd El-Halim Saif EL-Din, Yasmin Ahmed Elsharawy, Fatma Mohamed Elhussieny |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Nasal cavity
medicine.medical_specialty business.industry digestive oral and skin physiology education Mitomycin C Adhesion (medicine) Functional endoscopic sinus surgery medicine.disease Group B Surgery 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis medicine 030223 otorhinolaryngology business Synechia Endoscopic nasal surgery |
| Zdroj: | Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 21:154-158 |
| ISSN: | 2090-3405 |
| DOI: | 10.21608/ejentas.2020.26708.1189 |
| Popis: | Background: Synechia formation in a postoperative nasal cavity is a major factor for suboptimal clinical outcome in functional endoscopic sinus surgery (FESS). Nasal packs medicated with topical agents like mitomycin C have been shown to reduce the formation of synechiae in postoperative patients.Aim: To assess the role of mitomycin-c (MMC) in preventing synechia formation and ostial stenosis following endoscopic nasal surgery.Patients and Methods: This is a prospective comparative study performed at the department of Otorhinolaryngology, El-Zhraa University hospital from January 2018 to December 2019 to evaluate the effect of MMC in prevention of nasal adhesions after endoscopic nasal surgery. A total of fifty (50) patients of different age groups and both sexes were involved in the study and divided into two groups, each group include 25 patients, group A with applying MMC and group B without applying MMC.Results: In the MMC group, there was a reduction of synechia and crustration formation in group A that use MMC than group B without using MMC but with no significance.Conclusion: Mitomycin C (MMC) is safe and beneficial in decreasing adhesion formation after endoscopic nasal surgery. |
| Databáze: | OpenAIRE |
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