Comparative study of the effects of flurazepam and nitrazepam on sleep by 24-hour polygraphy

Autor:	Ikan Nakamura, Chikara Ogura, Kazuyoshi Nakasawa, Yoichi Umezawa, Hajime Ueda, Kazuaki Majima
Rok vydání:	1978
Předmět:	Pharmacology medicine.diagnostic_test Nitrazepam Flurazepam medicine.drug_class business.industry General Medicine Electroencephalography Sleep in non-human animals Nitrazepam 5 MG Hypnotic Anesthesia Healthy volunteers medicine Pharmacology (medical) Prolonged sleep business medicine.drug
Zdroj:	European Journal of Clinical Pharmacology. 13:413-418
ISSN:	1432-1041 0031-6970
DOI:	10.1007/bf00566318
Popis:	A new method, 24-hour polygraphy (EEG, EMG, and EOG), was applied not only to investigate the influence of hypnotics on night sleep, but to examine the precise influence on sleep-wake-fulness rhythm the day following administration. The hypnotics used were flurazepam 15 mg and nitrazepam 5 mg. The subjects were healthy volunteers, 5 men and 4 women, aged 20–50 years. The polygraphic record was made three times for each subject. Flurazepam prolonged sleep time (%) significantly (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fb3dae8e00b8ea348eba61b509ad3b00 https://doi.org/10.1007/bf00566318 Zobrazit plný text záznamu Full text from SpringerLink