ChemInform Abstract: Convergent Approach to Water Soluble Camptothecin Derivatives

Autor:	Hiroshi Akimoto, Koichiro Ootsu, Z.‐F. Xie
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Antitumor activity Water soluble chemistry medicine heterocyclic compounds General Medicine biological phenomena cell phenomena and immunity Aldehyde Combinatorial chemistry Camptothecin medicine.drug
Zdroj:	ChemInform. 27
ISSN:	0931-7597
Popis:	New water soluble camptothecin derivatives with excellent antitumor activity have been designed and synthesized. The synthetic approach includes an efficient route to 7-aminoethyl and 7-aminomethyl camptothecins using either N-Boc protected aminopropion(or aceto)aldehyde or N-methylacetamide as alkylating agents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fb366691d5c05ca14aa7e04498c625ce https://doi.org/10.1002/chin.199606243 Zobrazit plný text záznamu Plný text