| Popis: |
Toxicologists at 711 HPW/RHDJ have reviewed the 2013 document published by the Agency for Toxic Substances and Disease Registry (ATSDR) entitled Addendum to the Toxicological Profile for Jet Fuels (JP-5 and JP-8) (ATSDR, 2013). The full document Toxicological Profile for JP-5 and JP-8 , published in 1998 (ATSDR, 1998), is scheduled for update in FY14. A review of the Addendum identified concerns over the quality of a subset of studies summarized in the 2013 document and the potential inclusion of this subset in the 2014 update. The purpose of this special report is to provide information to supplement the FY14 update of the ATSDR Toxicological Profile for JP-5 and JP-8, and to present recommendations for data inclusion. The authors conclude that the exposure compounds and concentrations are unknown in studies published by the University of Arizona utilizing the DeVilbiss Ultra-Neb nebulizer exposure system. Therefore these studies are unsuitable for assessment of JP-8 risk. ATSDR should not handle these studies as key studies in their FY14 update. |
