LC-PDA-ORD Bioassay of S-(+) and R-(-) Colchicine on Rat Dried Blood Spots: Application to a Pharmacokinetic Study
| Autor: | T. Siva Rao, Marakada Sridevi, Challa Gangu Naidu, Bandaru Nagaraju |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Chromatography
medicine.diagnostic_test Spots Chemistry Normal phase 010401 analytical chemistry macromolecular substances biochemical phenomena metabolism and nutrition Hematocrit equipment and supplies 01 natural sciences 0104 chemical sciences 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pharmacokinetics medicine Bioassay Colchicine 030216 legal & forensic medicine Enantiomer Dried blood Earth-Surface Processes |
| Zdroj: | Analytical Chemistry Letters. 8:139-151 |
| ISSN: | 2230-7532 2229-7928 |
| DOI: | 10.1080/22297928.2017.1422802 |
| Popis: | A simple and sensitive normal phase liquid chromatographic method was developed and validated for quantification of Colchicine (COL) enantiomers on rat dried blood spots (DBS). The COL was extracte... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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