Description of six new HLA-B alleles in the 5C CREG including a B*58 intron two sequence

Autor:	Jennifer Ng, Carolyn Katovich Hurley, C.P. Gans, Robert J. Hartzman, W. Mitton
Rok vydání:	2002
Předmět:	Genetics Immunology Intron General Medicine Human leukocyte antigen Biology Biochemistry Molecular biology DNA sequencing HLA-B Immunology and Allergy Allele Gene
Zdroj:	Tissue Antigens. 59:145-147
ISSN:	0001-2815
DOI:	10.1034/j.1399-0039.2002.590214.x
Popis:	Five of the six novel HLA-B alleles described in this report contain polymorphic motifs previously reported in HLA-B alleles, suggesting an origin resultant from a gene conversion mechanism. The sixth allele, B*35012, contains a polymorphism previously unreported in HLA-B molecules. In addition to previously reported polymorphisms, B*5806 carries a previously unreported intronic substitution in a sequencing primer annealing site.
Databáze:	OpenAIRE
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