Impact of guidelines implemented in a Paris university hospital: application to the use of antiemetics by cancer patients

Autor:	Antoine Flahault, Bernard Milleron, Isabelle Debrix, L. Schwartz, Annie Becker, Alain Kanfer
Rok vydání:	1999
Předmět:	Pharmacology medicine.medical_specialty Pediatrics Palliative care business.industry Nausea medicine.drug_class Delphi method Cancer Drug Utilization Review University hospital medicine.disease Family medicine Medicine Antiemetic Pharmacology (medical) Medical prescription medicine.symptom business
Zdroj:	British Journal of Clinical Pharmacology. 48:616-622
ISSN:	0306-5251
DOI:	10.1046/j.1365-2125.1999.00048.x
Popis:	Aims To assess the impact with time of guidelines on antiemetic use in an 850-bed Paris university hospital with a high proportion of cancer patients. Methods Guidelines on the use of antiemetics available in cancer chemotherapy were drafted according to the Delphi technique. Their implementation was based upon a patient-specific antiemetic prescription form. To assess the impact of guideline implementation over time, discrepancies between current practice and the guidelines were compared before guideline implementation (between March and August 1995) and after implementation (between March and August 1997, and March and August 1998). Results Before the Delphi panel’s guidelines were implemented, 5-HT3 antagonists were inappropriately administered in 70% of cases. After guideline implementation, this proportion dropped significantly (P
Databáze:	OpenAIRE
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