A short and highly convergent approach for the synthesis of rutaecarpine derivatives

Autor: B. V. Subba Reddy, T. Prabhakar Rao, P. Pranathi, Shasi V. Kalivendi, B. Jagan Mohan Reddy, R. Anji Babu, B. Sridhar, T. Ramalinga Murthy
Rok vydání: 2015
Předmět:
Zdroj: RSC Advances. 5:27476-27480
ISSN: 2046-2069
Popis: A novel and highly convergent approach has been developed for the synthesis of quinazolinocarboline alkaloid, rutaecarpine, analogues by the condensation of anthranilamide with chloroaldehyde derived from tryptophol. This method also provides direct access to benzimidazocarbolines and quinazolinoisoquinolines. It is a shorter and metal-free approach which does not require any catalyst or additive to facilitate the reaction.
Databáze: OpenAIRE