Dietary saturated fatty acid composition has differential effects on HDL binding to Guinea Pig hepatic membranes
| Autor: | Emme C. K. Lin, Donald J. McNamara, Maria Luz Fernandez |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
Nutrition and Dietetics Endocrinology Diabetes and Metabolism Myristic acid Metabolism Palmitic acid chemistry.chemical_compound Endocrinology High-density lipoprotein chemistry Internal medicine Saturated fatty acid medicine lipids (amino acids peptides and proteins) Palm kernel oil Composition (visual arts) Stearic acid Food science |
| Zdroj: | Nutrition Research. 14:753-764 |
| ISSN: | 0271-5317 |
| DOI: | 10.1016/s0271-5317(05)80210-6 |
| Popis: | The effects of dietary saturated fatty acid composition on high density lipoprotein (HDL) metabolism in guinea pigs were investigated. Animals were fed semi-purified diets containing 15% (w/w) fat, either palm kernel oil (PK), high in lauric + myristic acids; palm oil (PO), high in palmitic acid; or beef tallow (BT), high in stearic acid. Intake of the PK diet resulted in the highest plasma total cholesterol level (P 125 I-HDL. While no differences in receptor affinity (K d ) due to dietary fat composition were found, HDL binding protein number (B max ) was highest in animals fed the BT diet (2.39±0.05 μg/mg), intermediate in the PK (1.98±0.07 μg/mg) and lowest in the PO group (1.69±0.07 μg/mg) (P max ) (r=−0.59, n=18, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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