| Autor: |
Matthew E Prekker, Brian E Driver, Stacy A Trent, Daniel Resnick-Ault, Kevin Seitz, Derek W Russell, Sheetal Gandotra, John P Gaillard, Kevin W Gibbs, Andrew Latimer, Micah R Whitson, Shekhar Ghamande, Derek J Vonderhaar, Jeremy P Walco, Sydney J Hansen, Ivor S Douglas, Christopher R Barnes, Vijay Krishnamoorthy, Jill J Bastman, Bradley Daniel Lloyd, Sarah W Robison, Jessica A Palakshappa, Steven Mitchell, David B Page, Heath D White, Alyssa Espinera, Christopher Hughes, Aaron M Joffe, J Taylor Herbert, Steven G Schauer, Brit J Long, Brant Imhoff, Li Wang, Jillian P Rhoads, Kelsey N Womack, David Janz, Wesley H Self, Todd W Rice, Adit A Ginde, Jonathan D Casey, Matthew W Semler |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMJ Open. 13:e068978 |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2022-068978 |
| Popis: |
IntroductionAmong critically ill patients undergoing orotracheal intubation in the emergency department (ED) or intensive care unit (ICU), failure to visualise the vocal cords and intubate the trachea on the first attempt is associated with an increased risk of complications. Two types of laryngoscopes are commonly available: direct laryngoscopes and video laryngoscopes. For critically ill adults undergoing emergency tracheal intubation, it remains uncertain whether the use of a video laryngoscope increases the incidence of successful intubation on the first attempt compared with the use of a direct laryngoscope.Methods and analysisTheDirEct versusVIdeo LaryngosCopE(DEVICE) trial is a prospective, multicentre, non-blinded, randomised trial being conducted in 7 EDs and 10 ICUs in the USA. The trial plans to enrol up to 2000 critically ill adults undergoing orotracheal intubation with a laryngoscope. Eligible patients are randomised 1:1 to the use of a video laryngoscope or a direct laryngoscope for the first intubation attempt. The primary outcome is successful intubation on the first attempt. The secondary outcome is the incidence of severe complications between induction and 2 min after intubation, defined as the occurrence of one or more of the following: severe hypoxaemia (lowest oxygen saturation Ethics and disseminationThe trial protocol was approved with waiver of informed consent by the single institutional review board at Vanderbilt University Medical Center and the Human Research Protection Office of the Department of Defense. The results will be presented at scientific conferences and submitted for publication in a peer-reviewed journal.Trial registration numberClinicalTrials.gov Registry (NCT05239195). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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