A New Ethical Dilemma For Hemodialysis Patients : Exposure To Diethyl Hexyl Phthalate
| Autor: | Ezzat M. Mohammad, Nermine Ibrahim, Amal M.H. Mackawy, Nevien S. S. Sakla |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
endocrine system
medicine.medical_specialty education.field_of_study biology business.industry medicine.medical_treatment Population Phthalate Albumin Urology Aspartate transaminase End stage renal disease chemistry.chemical_compound chemistry Alanine transaminase medicine biology.protein Hemodialysis education business Dialysis |
| Zdroj: | Mansoura Journal of Forensic Medicine and Clinical Toxicology. 18:97-111 |
| ISSN: | 1110-5437 |
| DOI: | 10.21608/mjfmct.2010.56180 |
| Popis: | Patients undergoing hemodialysis are exposed to medical devices containing di-ethylhexyl phthalate(DEHP). There is an ongoing discussion about the risks of DEHP exposure for the general population aswell as for specific subgroups in various medical settings. Due to the widespread use of DEHP in polyvinylchloride (PVC) medical devices and in life, this work is an essential step in such a way that the exposureamount of DEHP would be precisely determined in patients undergoing regular hemodialysis in orderto evaluate its significance as an integral part of the assessment of the risk of DEHP to human liver.Thirty subjects were involved in this work. Ten of them were healthy volunteers (n=10) as a controlgroup and twenty patients with end stage renal disease (ESRD) on regular hemodialysis (n=20). Twosamples were taken from all subjects, one prior to and one after the dialysis session, for measuring theserum levels of: alanine transaminase, aspartate transaminase and albumin, and the estimation of DEHPserum level by using high performance liquid chromatography (HPLC). Significant increases (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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