Incomplete differentiation of the cardiac valves
| Autor: | William C. Manion, Vincent J. Hyams |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Aortic valve
medicine.medical_specialty business.industry Heart malformation Hemodynamics All cardiac valves Surgery Lesion medicine.anatomical_structure Internal medicine Cardiac valve cardiovascular system Cardiology Medicine medicine.symptom Cardiology and Cardiovascular Medicine business Complication |
| Zdroj: | American Heart Journal. 76:173-182 |
| ISSN: | 0002-8703 |
| DOI: | 10.1016/0002-8703(68)90192-0 |
| Popis: | Incomplete differentiation of cardiac valves is a relatively common, but infrequently recognized and documented congenital malformation of the cardiac valve involving single, multiple, or all cardiac valves. A total of 197 cases were reviewed. This group comprises 5 per cent of the gross congenital hearts examined at the Armed Forces Institute of Pathology over the past 15 years. In some cases, the only cardiac abnormality was the valvular lesion, but the great majority of cases presented other associated single or multiple congenital cardiac anomalies. The lesion is believed to be caused by varying degrees of incomplete development of the cardiac valves from their embryonic state. An implication of the significance of this entity is indicated by the finding of varying degrees of ischemic myocardial damage associated with aortic valve involvement. This complication is believed to be the result either of coronary hemodynamic disturbance or of local myocardial biochemical imbalance. Clinical awareness of incomplete differentiation of the valve and its possible complications should be stressed because of the obvious hazards of corrective operation in these hearts. |
| Databáze: | OpenAIRE |
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