Botulinum toxin type A: applications in urogynaecology

Autor: Angamuthu S Arunkalaivanan, Deepali Sinha
Rok vydání: 2006
Předmět:
Zdroj: The Obstetrician & Gynaecologist. 8:177-180
ISSN: 1467-2561
DOI: 10.1576/toag.8.3.177.27254
Popis: Although not yet licensed, intradetrusor botulinum toxin type A injection has a potential role in the treatment of urogynaecological conditions, the most important of which is intractable urodynamically-proven detrusor overactivity. This article discusses the mechanism of action, potential indications for use, preoperative management and side effects. The techniques used are also described. Botulinum toxin type A injection has an excellent safety and tolerability profile across a wide range of urological uses, but there is a need for further evaluation with randomised, placebo-controlled trials.
Databáze: OpenAIRE