Topical Review Article: Medulloblastoma: I. Clinical, Diagnostic, and Therapeutic Overview
| Autor: | Bernd W. Scheithauer, Robert V. Groover, Gary M. Miller, Fredric B. Meyer, William A. Smithson, Frank H. Tomlinson, Edward G. Shaw |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Medulloblastoma
medicine.medical_specialty Pathology business.industry medicine.medical_treatment Cerebellar Neoplasm medicine.disease Developing nervous system Radiation therapy Topical review 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Pediatrics Perinatology and Child Health Epidemiology medicine Combined Modality Therapy Neurology (clinical) Intensive care medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Child Neurology. 7:142-155 |
| ISSN: | 1708-8283 0883-0738 |
| DOI: | 10.1177/088307389200700203 |
| Popis: | Medulloblastoma, the most common embryonal tumor of the central nervous system, affects both children and adults. It poses a significant therapeutic challenge in that age-dependent differences exist, not only in their pathobiology, but in the efficacy of chemotherapy and radiotherapy. This is particularly the case in very young children, whose still developing nervous system exhibits a low tolerance to radiotherapy. We review the epidemiology, clinical presentation, radiologic features, and current therapeutic concepts relative to this unique neoplasm. Efforts are made to highlight clinical controversies. ( J Child Neurol 1992;7:142-155). |
| Databáze: | OpenAIRE |
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