Do Outcomes from Transcatheter Aortic Valve Implantation Vary According to Access Route and Valve Type? The UK TAVI Registry

Autor: Paul D. Baxter, Chris P Gale, David Hildick-Smith, Philip MacCarthy, Daniel J. Blackman, David Cunningham, Neil E. Moat, Peter Ludman, Uday Trivedi, Mark A. de Belder
Rok vydání: 2013
Předmět:
Zdroj: Journal of Interventional Cardiology. 27:86-95
ISSN: 0896-4327
DOI: 10.1111/joic.12084
Popis: Objectives To determine whether outcomes from transcatheter aortic valve implantation (TAVI) vary according to access route and valve type in a real-world population. Background Registry and uncontrolled trial data have found that patients undergoing nonfemoral TAVI have higher early and late mortality. It is not clear whether worse outcomes relate directly to access route. There have been no direct comparisons of outcomes according to valve type. Methods Data were collected prospectively on 1,620 patients undergoing TAVI in the UK and compared in 4 groups: SAPIEN transfemoral (TF); SAPIEN transapical (TA); CoreValve TF, CoreValve subclavian. Univariable and multivariable regression analysis was performed to identify independent predictors of mortality. Results Mortality in patients undergoing SAPIEN TAVI via a TA approach was higher than with TF at 30 days (11.2% vs. 4.4%, P
Databáze: OpenAIRE