| Autor: |
Evan M. Sherbrook, Adrian G. Amador, Tehshik P. Yoon |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
ChemInform. 47 |
| ISSN: |
0931-7597 |
| Popis: |
Control of stereochemistry in photocycloaddition reactions remains a substantial challenge; almost all successful catalytic examples to date have involved [2 + 2] photocycloadditions of enones. We report a method for the asymmetric [3 + 2] photocycloaddition of aryl cyclopropyl ketones that enables the enantiocontrolled construction of densely substituted cyclopentane structures not synthetically accessible using other catalytic methods. These results show that the dual-catalyst strategy developed in our laboratory broadens synthetic chemists' access to classes of photochemical cycloadditions that have not previously been feasible in enantioselective form. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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