The process of continuous production and isolation of coproporphyrin

Autor: Kotal P, Jan Sperl, Milan Jirsa, V. Kordač
Rok vydání: 1988
Předmět:
Zdroj: Biotechnology Letters. 10:273-276
ISSN: 1573-6776
0141-5492
DOI: 10.1007/bf01024418
Popis: The production of coproporphyrin from glucose and urea has been achieved by semi-aerobic culture ofSaccharomyces cerevisiae. The cells were entrapped in alginate gel and packed into a column reactor for continuous long-term process. The porphyrins were isolated and simultaneously concentrated from the effluent by liquid-solid phase extraction, purified by liquid chromatography and finally crystallized. Using the process described the final product of high purity was obtained.
Databáze: OpenAIRE