New Aspects of the Aromatic Photosubstitution with Iodopyridines

Autor:	Koh-ichi Seki, Yuichi Kanaoka, Masanao Terashima, Kazue Ohkura
Rok vydání:	1993
Předmět:	Electron pair Chemistry Radical Free-radical reaction chemistry.chemical_element General Chemistry General Medicine Electrophilic aromatic substitution Photochemistry Nitrogen Toluene chemistry.chemical_compound Drug Discovery Molecular orbital Carbon
Zdroj:	Chemical and Pharmaceutical Bulletin. 41:1920-1924
ISSN:	1347-5223 0009-2363
Popis:	Reactive entities in the photoreaction of 2-, 3- and 4-iodopyridines with substituted benzenes were investigated; 3- and 4-pyridylation could be explained in terms of radical reaction, while the 2-pyridyl cation was an important intermediate in the 2-pyridylation. The importance of the unshared electron pair of the nitrogen adjacent to the radical carbon for the conversion of the 2-pyridyl radical initially produced into the cation is discussed on the basis of molecular orbital (MO) calculations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fa4b959914a19a10632c6b30f6ad1e75 https://doi.org/10.1248/cpb.41.1920 Zobrazit plný text záznamu