Functionalization of 2-Amino-6-thioxouracil as a Precursor for the Synthesis of Some Novel Pyrimidine Heterocycles

Autor:	M. H. M. Abd El-Azim, W. Farid, Mohamed G. Assy, Atef M. Abdel Hamid
Rok vydání:	2021
Předmět:	Antifungal chemistry.chemical_compound Pyrimidine chemistry medicine.drug_class medicine Surface modification General Chemistry Combinatorial chemistry
Zdroj:	Russian Journal of General Chemistry. 91:904-909
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363221050212
Popis:	In this study, 2-amino-6-thioxouracil is utilized as a precursor for the synthesis of novel functionalized and fused pyrimidine heterocycles including tetrazolopyrimidines, imidazolopyrimidines and triazolopyrimidines. Some of the newly synthesized compounds show moderate to good antibacterial and antifungal activities against the tested microorganisms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fa4553057966fbb7dca3fd0c73ff6091 https://doi.org/10.1134/s1070363221050212 Zobrazit plný text záznamu Plný text ve formátu PDF