A case of juvenile lupus with an extremely rare dendritic cell malignancy: Interdigitating dendritic cell sarcoma – coexistence or paraneoplastic manifestation?
| Autor: | Meher Lakshmi Konatam, Megha S Uppin, Deepika Ponnuru, Liza Rajasekhar, D Phani Kumar, Pratyusha Rajavarapu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Autoimmune disease
Pathology medicine.medical_specialty Systemic lupus erythematosus business.industry Autoantibody Cancer Inflammation Dendritic cell medicine.disease Malignancy Rheumatology immune system diseases Interdigitating dendritic cell sarcoma medicine medicine.symptom skin and connective tissue diseases business |
| Zdroj: | Indian Journal of Rheumatology. 16:89 |
| ISSN: | 0973-3698 |
| DOI: | 10.4103/injr.injr_124_19 |
| Popis: | Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease, characterized by circulating autoantibodies, widespread inflammation, and tissue destruction. The association between cancer and SLE is intriguing in view of their common pathophysiological pathways. It is established that there is an increased risk for overall malignancies in SLE, with standardized incidence ratios ranging from 1.14 to 3.6. Hematological malignancies are more common than solid organ malignancies in SLE. Malignancy when associated with lupus usually follows the diagnosis, but can occur concurrently or even predate the diagnosis of SLE. Neoplasms of dendritic cells (DCs), the key antigen-presenting cells, are rare, and they account for |
| Databáze: | OpenAIRE |
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