Synthesis of 4-aroyl-5-nitro-1H-imidazoles and 4-aroyl-5-aminoimidazoles

Autor: J. Donald Albright, Daniel B. Moran
Rok vydání: 1986
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 23:913-919
ISSN: 1943-5193
0022-152X
DOI: 10.1002/jhet.5570230350
Popis: The reaction of α-(aryl)-4-morpholineacetonitriles (masked aroyl anion equivalents) with N-protected 4(5)-bromo-5(4)-nitro-1H-imidazoles gave 4-aroyl-5-nitroimidazoles which were reduced to afford 4-aroyl-5-aminoimidazoles.
Databáze: OpenAIRE