Urinary iodine excretion in Egyptian females with nodular goiter

Autor: Rokaya Abd El Aziz, Tarek Heshmat, Randa Salam
Rok vydání: 2014
Předmět:
Zdroj: Endocrine Abstracts.
ISSN: 1479-6848
DOI: 10.1530/endoabs.35.p959
Popis: Background: Iodine is needed for the production of thyroid hormone. The best way to determine iodine deficiency across a large population is to measure the amount of iodine in urine sample. The aim of this work: is to measure the iodine excretion in patients with thyroid nodules in comparison to normal control subjects Subjects and methods: Eighty females were chosen from the outpatient clinic of Diabetes and Endocrine Center in Kasr El Aini hospital, Cairo University, with thyroid disorder. History taking, clinical examination, thyroid ultrasound, thyroid function test, urinary iodine excretion was done to all participants Results: showed that urinary iodine excretion in patients with multinodular and single nodule is significantly lowered than in control subjects Conclusion: Our results showed statistically significant lower urinary iodine excretion (22.6 to 30.6 μg/L) in all patients either with single or multiple nodular goiter with hypothyroidism or euthyroid state. Therefore, iodine deficiency contributes to development of thyroid nodules in Egyptian females.
Databáze: OpenAIRE