Atriopeptins. III. Synthesis and biological activity studies of α-r-ANF, AP-II, AP-III and des-Ser5-Ser6-AP-II
Autor: | Sergei V. Zhukovskii, Mikhail V. Ovchinnikov, Vinogradov Valentin A, Zhanna D. Bespalova, Mikhail I. Titov, Aleksandr S. Molokoedov, N.V. Korobov, Inna V. Revenko |
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Rok vydání: | 1989 |
Předmět: | |
Zdroj: | Collection of Czechoslovak Chemical Communications. 54:796-802 |
ISSN: | 1212-6950 0010-0765 |
DOI: | 10.1135/cccc19890796 |
Popis: | Starting from previously synthesized atriopeptin fragments, peptides α-r-ANF, AP-II, AP-III and des-Ser5-Ser6-AP-II were prepared using complex F. The acetamidomethyl protecting group on cysteine was removed simultaneously with the cyclization. Biological activity of atriopeptin was evaluated. |
Databáze: | OpenAIRE |
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