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Poor sleep quality and sleep disturbances (including insomnia and sleep apnoe) have been identified as risk factors for developing Alzheimer’s disease (AD) (Shi et al., 2019; Wu et al., 2019). Improving sleep quality may decelerate or even prevent the course of the disease and improve cognitive symptoms and AD biomarkers (e.g., beta amyloid) (Xie et al., 2013). Our aim is to conduct a systematic review analyzing which kinds of interventions (e.g., behavioral or medical) lead to which kinds of improvements or decelerations. References: Shi, L., Chen, S.-J., Ma, M.-Y., Bao, Y.-P., Han, Y., Wang, Y.-M., … Lu, L. (2018). Sleep disturbances increase the risk of dementia: A systematic review and meta-analysis. Sleep Medicine Reviews, 40, 4–16. Wu, H., Dunnett, S., Ho, Y. S., & Chang, R. C. (2019). The role of sleep deprivation and circadian rhythm disruption as risk factors of Alzheimer's disease. Frontiers in neuroendocrinology, 54, 100764. https://doi.org/10.1016/j.yfrne.2019.100764 Xie, L., Kang, H., Xu, Q., Chen, M. J., Liao, Y., Thiyagarajan, M., … Nedergaard, M. (2013). Sleep drives metabolite clearance from the adult brain. Science, 342(6156), 373–377. |
