Nickel-catalyzed cross-coupling of silyl enol ethers with grignard reagents. Regio- and stereocontrolled synthesis of olefins

Autor:	Yoshio Katsuro, Tamio Hayashi, Makoto Kumada
Rok vydání:	1980
Předmět:	Reaction conditions Silylation Organic Chemistry Regioselectivity chemistry.chemical_element Biochemistry Enol Medicinal chemistry Catalysis chemistry.chemical_compound Nickel chemistry Reagent Drug Discovery Organic chemistry
Zdroj:	Tetrahedron Letters. 21:3915-3918
ISSN:	0040-4039
DOI:	10.1016/0040-4039(80)80215-2
Popis:	The substitution of the siloxy group in silyl enol ethers with Grignard reagents to form olefins is accomplished by use of nickel acetylacetonate or phosphine-nickel complexes as catalysts, the stereo- and regiochemistry of coupled olefins depending upon the nature of the catalyst and reaction conditions employed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fa0d426b1a5e8bf58cc9393b1265e353 https://doi.org/10.1016/0040-4039(80)80215-2 Zobrazit plný text záznamu