Diagnostic Status of Chronic Kidney Disease in China – Results from 976,409 Individuals with Electronic Health Records

Autor: Chao Yang, Jinwei Wang, Jian Du, Beiyan Bao, Luxia Zhang, Xiaoyu Sun, Suyuan Peng, Guilan Kong, Huai-Yu Wang, Yu Zhao, Zhengyue Chen, Guo-hui Ding
Rok vydání: 2020
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
DOI: 10.2139/ssrn.3692417
Popis: Background: As a major public health challenge, the diagnostic status of chronic kidney disease (CKD) in developing countries, such as China, remains unclear. Methods: Adults with electronic health records (EHRs) from May 1st, 2008 to December 31st, 2019 in Yinzhou, China were included. CKD was defined as having persistently reduced estimated glomerular filtration rate (eGFR), albuminuria/proteinuria, hematuria, or a history of CKD. The CKD stage (G1-G5) was defined by eGFR. The diagnosis showing primary cause or CKD with stage was analyzed through relevant international classification of diseases-10(ICD-10) codes. The specialty of doctors who administered the serum creatinine (SCr) tests and who made the primary-cause/CKD-staging diagnosis was analyzed. The performance of each CKD-staging code was assessed through sensitivity, specificity, and accuracy. Findings: Altogether 75,147 CKD patients with complete data were identified from 976,409 individuals. Of these patients, 46,150(61·4%) had no any CKD-related codes; 6,857(35·7%) were merely labelled with primary-cause codes; and only 2,140(2·9%) were labelled with CKD-staging codes. The majority of CKD patients received SCr tests from non-nephrologists (51·6%-91·1%) whereas CKD-staging diagnoses were mainly from nephrologists (52·3%-64·8%). Only 3 of 42 general hospitals had nephrologists. The CKD-staging codes had high specificity (>99·0%) but low sensitivity even in the advanced stages(G3-G4
Databáze: OpenAIRE