Differential morphological responses to selection for high voluntary wheel running in the scapula and os coxae of mice (17.1)

Autor: Theodore Garland, Genesis Ordonez, Heidi Schutz
Rok vydání: 2014
Předmět:
Zdroj: The FASEB Journal. 28
ISSN: 1530-6860
0892-6638
DOI: 10.1096/fasebj.28.1_supplement.17.1
Popis: Previous work has shown that the morphology of the scapula and ox coxae vary with locomotor differences. In addition, studies have also shown that chronic exercise produces a variety of long bone responses, including increased bone diameter and mass. Similar studies to voluntary exercise in flat bones, such as the major girdle elements (e.g. scapula, os coxae [hip bones]), are scarce, but show that the morphology of these elements may also respond to different forms of locomotor activity. We used laboratory mice from 4 replicate lines bred for high voluntary wheel running (HR) and 4 non-selected control (C) lines to examine responses in these elements to 21 generations of selection for high voluntary wheel running and 8 weeks of a wheel/ no-wheel treatment. Bone masses were taken and geometric morphometric techniques were employed to generate quantitative descriptors of 2D scapular and os coxae shape, centroid size, and a series of linear measurements. From the linear and mass data, we calculated ratios u...
Databáze: OpenAIRE
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