Drug Carriers in The Delivery and Release of Hydroxychloroquine by Biopolymer

Autor: Layth S. Jasim Al-Hayder, Mohammed kassim. Al-Hussainawy
Rok vydání: 2023
DOI: 10.21203/rs.3.rs-2656912/v1
Popis: The successful creation of several unique and intelligent drug delivery systems with improved therapeutic effectiveness, improved patient compliance, and new developments and research in the realm of biopolymers guides cost effectiveness. Several biodegradable polymers are widely employed in the drug delivery industry because they are biologically broken down inside the body into non-toxic components. The design of diverse drug delivery systems based on biopolymers can benefit from a comprehensive understanding of the possible qualities of biopolymers, including extraction techniques and environmentally friendly manufacturing, chemistry, surface properties, rheology, bulk properties, biocompatibility, and biodegradability. Accordingly, new biopolymers were synthesized by free radical and cross-linked molecules and their physical and chemical properties were studied, and some comprehensive examinations were conducted for the task of research, such as FT-IR-EDX, XRD, SEM, TEM, TGA, and BET-BJH. Good results were obtained for adsorption and releasing the adsorbed drug into the aqueous solution with a percentage of 20% at pH 2 and 3% at pH 7, 10. The divorce rate was high when there were different concentrations of salt.
Databáze: OpenAIRE