Advancements in Cancer Therapeutics
| Autor: | Aysen E. Ozel, Bilge Bicak, Serda Kecel Gündüz |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty business.industry Cancer 02 engineering and technology 021001 nanoscience & nanotechnology medicine.disease Cancer treatment 03 medical and health sciences 0302 clinical medicine Targeted drug delivery 030220 oncology & carcinogenesis Internal medicine medicine 0210 nano-technology business |
| DOI: | 10.4018/978-1-7998-6530-8.ch013 |
| Popis: | Targeted drug delivery in cancer treatment is a very convenient method for increasing the effectiveness of drugs and reducing their toxic side effects. Nano drug delivery systems have unique physical, chemical, mechanical, and optical properties. Nanoparticles, which have large surface areas and functional groups for the binding of therapeutic agents, benefit the drug distribution with nanoparticle formulations and can provide new features. They also enable personal oncology for diagnosis and treatment, which is appropriate for the personal molecular profile structures of cancer patients. The tumor-targeted active substances are attached to nanoparticles and the active substance loaded nanoparticles are targeted to the tumor area; these nanoparticles can be used with a high tendency to bind and specificity, to target tumor antigens or vessels. This chapter, besides traditional chemotherapy and radiotherapy methods in the field of cancer treatment, is aimed to give information about targeted drug delivery systems for cancer cell targeting without damaging normal tissues. |
| Databáze: | OpenAIRE |
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