Metastatic breast cancer to colon: An unusual site of metastasis with a review of literature
| Autor: | Masoud Sadeghi, Farhad Amirian, Parham Nejati, Mazaher Ramezani |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Urinary system Ductal carcinoma medicine.disease Metastatic breast cancer General Biochemistry Genetics and Molecular Biology Metastasis Lesion Breast cancer Progesterone receptor medicine Immunohistochemistry medicine.symptom skin and connective tissue diseases business |
| Zdroj: | Biomedical Research and Therapy. 6:3088-3092 |
| ISSN: | 2198-4093 |
| Popis: | Gastrointestinal (GI) metastasis is very rare in patients with breast cancer (BC). This study reports a case with colon carcinoma metastasis originated from breast cancer in Western Iran. A 37-yearold female was diagnosed with infiltrating ductal carcinoma. Immunohistochemistry (IHC) results showed positive estrogen receptor, progesterone receptor, HER2 scored 2 out of 3, Ki-67 in 30% of tumor cells and P53. The patient was re-admitted two times with urinary and GI symptoms, positive tumor markers and thick colon wall. Samples from the colon were collected to test for metastasis. The pathologist reported metastatic breast ductal carcinoma spread to the colon. The IHC showed CK7, CK20, GCDFP15, ER and PR positivity. In conclusion, this IHC panel can be considered as the differential and diagnostic markers for malignant GI lesion originated from breast cancer. |
| Databáze: | OpenAIRE |
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