Glycolytic and Oxidative Energy Metabolism and Contraction Characteristics of Intact Human Muscle

Autor: L. Edström, Kent Sahlin, H. Sjöholm, Eric Hultman
Rok vydání: 2008
Předmět:
Zdroj: Ciba Foundation Symposium 82-Human Muscle Fatigue: Physiological Mechanisms
DOI: 10.1002/9780470715420.ch2
Popis: It is proposed that glycolytic rate may be measured as lactate accumulation after electrical stimulation of the quadriceps femoris muscle under anaerobic conditions. The ratio of glucose 6-phosphate to lactate is an internal monitor of the glycolytic pathway. The phosphocreatine/lactate ratio links glycolysis and the creatine kinase reaction and could be used to distinguish abnormalities in energy metabolism. The rate of resynthesis of phosphocreatine after stimulation when the circulation is restored should be measure of oxidative phosphorylation. The relaxation rate seems to be a mechanical index of the metabolic state of the muscle.
Databáze: OpenAIRE